Abstract Background RNA viruses including arthropod-borne viruses (arboviruses) exist as highly genetically diverse mutant swarms within individual hosts.A more complete understanding of the phenotypic correlates of these diverse swarms is needed in order to equate RNA swarm breadth and composition to specific adaptive and evolutionary 1.29x4 outco
Core transport modelling of the DTT full power scenario using different fuelling strategies
A theory-based integrated prowler 3410 modelling work of plasma response to deuterium fuelling in the new Divertor Tokamak Test facility (DTT) is performed, using the 1.5D transport code JETTO with the quasi-linear anomalous transport model QuaLiKiz for the core region.The full power DTT scenario E1 is investigated.It is characterised by 28.8 MW of
The Effect of Psychotropic Drugs as a Performance Influencing Factor on Human Reliability Assessment
The increasing use/abuse of psychotropic drugs is an alarming social phenomenon with repercusions in many areas, especially in reliability engineering.The aim of this paper is to present a method developed by a multidisciplinary team composed of ergonomists, psychiatrists, information technologists, and reliability engineers to quantitatively consi
Circ_0000006 and circ_0000160 regulate hsa-let-7e-5p/UBQLN4 axis in aortic dissection progression.
Aortic aneurysms (AA) and aorta dissection (AD) are life-threatening conditions with a rising incidence and high mortality rate.Recent research has linked non-coding RNAs to the regulation of AA and AD progression.In this study, we performed circRNA sequencing, microRNA (miRNA) sequencing, and messenger RNA (mRNA) sequencing on plasma samples from
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro
IntroductionRespiratory syncytial virus (RSV) remains a major international public health concern.However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.In this study, natural products were screened to identify novel anti-RSV inhibitors.MethodsThe antiviral effect of 320 compounds on RSV in HEp-2 cel