Cooperative interactions in the West Nile virus mutant swarm

Abstract Background RNA viruses including arthropod-borne viruses (arboviruses) exist as highly genetically diverse mutant swarms within individual hosts.A more complete understanding of the phenotypic correlates of these diverse swarms is needed in order to equate RNA swarm breadth and composition to specific adaptive and evolutionary 1.29x4 outco

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Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro

IntroductionRespiratory syncytial virus (RSV) remains a major international public health concern.However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.In this study, natural products were screened to identify novel anti-RSV inhibitors.MethodsThe antiviral effect of 320 compounds on RSV in HEp-2 cel

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